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Prostrate Cancer Hormone Treatment Brings Other Health Risks
 One
of the major treatments for prostrate cancer involves blocking the secretion of testosterone. This is usually done in two methods, either by
removing the testes, or through hormone therapy in which the secretion of testosterone is inhibited by chemical means.
As it is widely observed, most men prefer the latter method over the former. The removal of testes is a bit too much for these people to digest. And, there lies the twist!
Recent studies conducted by scientists have confirmed that regular doses of
gonadotropin-releasing hormone (GnRH) agonist injections – the chemical used in hormone therapy - puts patients at a greater risk of developing cardiovascular diseases and diabetes mellitus.
Based on the observations made in the study, the articles of which had been published in the
Journal of Clinical Oncology, the study author, Ms. Nancy Keating, at Harvard School, adds that while men with
prostrate cancer usually have high 5 year survival rates, those being treated with
GnRH hormone therapy is showing even higher non-cancer mortality rates as well, as opposed to normal healthy men. For the patrons of GnRH agonist injections, this is bad news indeed.
In fact, it is not the first time that gonadotropin-releasing hormone agonist injections are coming under the scanner. Earlier studies conducted on the side effects of the chemical have concluded that
gonadotropin-releasing hormone (GnRH) plays a major role in causing obesity and insulin resistance, a precursor to the ailment, diabetes mellitus. The recent study further strengthens this side effect theory of
GnRH.
The findings show that people with regional or local prostrate cancer undergoing
gonadotropin-releasing hormone agonist injections have 44% higher risk of developing diabetes mellitus and 16% more chances of developing coronary heart ailments than those who are treated in other means.
Mr. Mathew Smith, the co-researcher of Ms. Nancy, points out that given the serious nature of the findings, now the doctors must think twice before prescribing GnRH agonist injections to patients, even if they prefer hormone therapy over testes removal.
The study author further adds that lot of men are undergoing hormone therapy these days, and for them, even after complete recovery from prostrate cancer, the risks associated with
GnRH agonist injections may continue to trouble them all through their lives. Hence, those preferring
GnRH agonist injection therapy must be prepared mentally and physically for this ordeal as well.
Summing up all the facts and findings, the study concludes that it is important for all prostate cancer patients to be learnt and educated about the risks associated with
GnRH agonist injections, and they must consider weight loss and
exercise to help lower the risk while undergoing and post-treatment. For the old aged, but, testes removal is the risk free bet than
GnRH treatments.
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